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Covaris AFA® for FFPE Extraction
 Extract high-quality DNA, RNA, Protein and Chromatin

Adaptive Focused Acoustic® energy deparaffinizes the sample and gently hydrates and homogenizes the tissues. Benefits of this include:
  • Superior DV200 values and Functional RNA Quantity scores allow detection of gene fusions
  • Significantly lower % QNS (Quantity Not Sufficient)
  • Elimination of organic solvents from protocol
  • Automation compatible 
  • Kit available to extract RNA and DNA from the same sample
  • RNAseq data from FFPE are comparable to RNA extracted from Fresh Frozen samples for Whole Genome Sequencing
  • Extracted DNA results in superior percent-on-target during targeted sequence analysis


Covaris AFA for Microbial Cell Lysis &
Biomolecule Extraction

High quality extractions from a variety of microorganisms



Covaris AFA for Whole Blood Extractions
Extract high quality DNA and RNA from Whole Blood

  • Fully automatable with robots (LE220R-plus, LE220Rsc) or liquid handlers (R230)
  • Extract HMW DNA and RNA with truPOPTM Extraction Buffer
  • Scalable to 384 well plates
Featured Publication

Clinical whole-genome sequencing from routine formalin-fixed, paraffin-embedded specimens: pilot study for the 100,000 Genomes Project

Robbe et. al. found that using Covaris truXTRAC FFPE kits to extract DNA from cancer samples produced optimized and favorable results as an alternative source of DNA for WGS cancer diagnostics if flash frozen tissue was unavailable.

Citation: Robbe P, Popitsch N, Knight SJL, et al. Clinical whole-genome sequencing from routine formalin-fixed, paraffin-embedded specimens: pilot study for the 100,000 Genomes Project. Genet Med. 2018;20(10):1196-1205.

Application Notes

Cell Lysis and Extraction of Biomolecules from Eukaryotic and Prokaryotic Cells Powered by AFA-energetics®


AFA-energetics®-Mediated DNA Extraction from Yeast and Bacteria Using Scanning in a Labcyte 384-well Plate

Contact Covaris Today!




Upcoming Conferences

AACR 2019March 29 to April 3

Visit our team at Booth #3328

Exhibitor Spotlight Presentation:

Monday, April 1st, 2019 at 10:00 AM – 11:00 AM in Theater C
Speaker: Shawn Levy, PhD Director, Genomic Services Laboratory,
HudsonAlpha Institute for Biotechnology
Title: Co-extraction of RNA and DNA by Covaris Adaptive Focused Acoustics (AFA) Enables Genome-scale Analysis for Most FFPE Tissues
Contact Us:
Tel: +1 781-932-3959
Fax: +1 781-932-8705

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