Active paraffin removal from FFPE tissues with Adaptive Focused Acoustics
Covaris has developed a novel method of active paraffin removal from Formalin-Fixed, Paraffin Embedded (FFPE) tissues utilizing Adaptive Focused Acoustics (AFA) technology. When an AFA treatment is applied to a FFPE sample, the paraffin is separated from the tissue sample by emulsification. This is an active mechanical process eliminating the use of hazardous organic solvents, or oils. It results in a robust and easily automatable workflow, which generates consistent DNA yield sample to sample, and improves the quality of the extracted nucleic acids; two parameters essential for clinical research and diagnostics.