Covaris Focused-ultrasonicators are engineered to meet your sample preparation needs by delivering highly-controlled and focused acoustic energy to your samples. Focused-ultrasonicators standardize sample prep for a variety of application areas including: DNA shearing for Next-Gen sequencing, RNA and protein extraction, Chromatin shearing, cell lysis, tissue to biomarker, compound management, formulations, and more.
AFA (Adaptive Focused Acoustics™) technology is non-contact and isothermal, providing processing performance and recoveries unmatched by any other sample preparation methodology available today. Covaris Focused-ultrasonicators range from personal use to high-throughput systems including, single-sample, multi-sample, and parallel-processing configurations. All Focused-ultrasonicators are powered by SonoLab, Covaris’ proprietary software.
The chart below will help you to choose the Covaris Focused-ultrasonicator that is right for your application. For additional information, please contact us.
Ideal: lysis and extraction
Ideal: shearing and mixing
LE220R-plus (non-robotic version available)
R230 AFA Revolution (designed for liquid handlers)
DNA/RNA/Chromatin Shearing DNA/RNA/Total NA/Protein Extraction from FFPE cfDNA Extraction from Plasma DNA Extraction from Dried Blood Spots Cell lysis: mammalian, bacterial, yeast Tissue lysis and extraction
DNA/RNA/Chromatin Shearing DNA/RNA/Total NA/Protein Extraction from FFPE cfDNA Extraction from Plasma DNA Extraction from Dried Blood Spots High Molecular Weight DNA Extraction Cell Lysis
Cell Lysis: mammalian, bacterial, yeast High Molecular Weight DNA Extraction DNA/RNA/Total NA/Protein Extraction from FFPE DNA Shearing Sample processing: bead mixing Compound screening Hit validation Target ID & validation
DNA Shearing Bead mixing/pellet resuspension High Molecular Weight DNA Extraction Mammalian cell lysis Compound screening Hit validation Target ID & validation