Designed for extreme turbulence and precise temperature control in a non-contact environment
* flow cell OR batch vessel
Ibuprofen with AFA produces 700 nm particles while untreated samples are large, uneven clumps.
Particle Count vs. PIP
Features & Benefits
AFA-Nanocrystal™ Production Batch-scale (2mL) Felodipine Preparation Protocol
AFA-Nanocrystal™ Production Batch-scale (2mL) Indomethacin Preparation Protocol
AFA-Nanocrystal™ Production Batch-scale (2mL) Cinnarizine (CNZ) Preparation Protocol
Preparation of Felodipine Nanosuspension (2 ml) by crystallization through AFA technology
Continuous nanoparticle production using focused acoustics Continuous flow AFA-Nanocrystal™ production using a solvent/antisolvent method. Poster abstract for 2015 AIChE Annual Meeting Nov 8-13, Salt Lake City, UT
Controlling Crystallization with Adaptive Focused Acoustics Poster: He et al., 2013. Flow Chemistry Congress, Boston, MA
Crystal Nucleation of Poorly Soluble Drugs: Experimental Results and New Knowledge Master’s Degree Thesis: Alexandra Franzén, Department of Chemistry, Lund University (2011).
WO2011/102787 A1 Patent: Lindfors et al., 2011. Process for Preparation of Crystalline Nano-particle Suspensions.
Case Study 1: Crystallization by Solvent / Anti-solvent
Case Study 2: Cooling Crystallization
Tel: +1 781-932-3959
Fax: +1 781-932-8705
To place orders: CustomerService@covaris.com
Protocol, method and application support: ApplicationSupport@covaris.com
Service and support for your Covaris instruments and consumables: TechSupport@covaris.com