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cfDNA Yield and DNA Integrity (Alu115/247 ratio) Reflect the Increase in Complexity of Actively Extracted cfDNA
DNA integrity index as determined by qPCR (Alu115/Alu247 ampliﬁcation ratios) from cfDNA isolated by Competitor Q (black) and truXTRAC cfDNA from Plasma kits (blue.) Three of seven shown donors display signiﬁcantly diﬀerent Alu115/Alu247 ratios as compared to the market leading cfDNA extraction kit.
cfDNA complexity of the truXTRAC cfDNA isolates is reﬂected in the electropherograms of the (Fragment Analyzer, AATI). cfDNA isolated with either truXTRAC or a leading cfDNA extraction kit are analyzed on the Fragment Analyzer (AATI).
Electropherogram of extracted cfDNA using Competitor Q (black trace) and truXTRAC (blue trace) of donor KP49089 .
|Part #||Product Name||Description|
|520234||truXTRAC cfDNA from
Plasma Kit – Column
|The truXTRAC cfDNA kit contains AFA-optimized reagents and consumables required for extraction of cfDNA from up to 1 ml plasma and with column-based purification (bead-based purification under development).|
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